Santo Domingo de la Calzada is a municipality in La Rioja, Spain, situated on the banks of the Oja River. Its name refers to its founder, Dominic de la Calzada, who built a bridge, hospital, and hotel here for pilgrims on the Way of St. James. The town's Cathedral of Santo Domingo de la Calzada is dedicated to him.
Gustavo Bueno was born here in 1924.